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HBEGF — JUN
Text-mined interactions from Literome
Fu et al., Proc Natl Acad Sci U S A 1999
(Cell Transformation, Neoplastic) :
In this system, induction of
v-Jun is
followed within 1 hr by elevated levels of
HB-EGF
Park et al., Am J Physiol 1999
:
AP-1 mediates stretch induced expression of
HB-EGF in bladder smooth muscle cells
Koh et al., J Biochem 2001
:
Electrophoretic mobility shift assay also showed the
involvement of
AP-1 in
HB-EGF gene expression by glucose
Zenz et al., Dev Cell 2003
(Genetic Predisposition to Disease...) :
Thus, using three experimental systems, we show that EGFR and
HB-EGF are
regulated by
c-Jun , which controls eyelid development, keratinocyte proliferation, and skin tumor formation
Wang et al., Oncogene 2007
(Neoplasms) :
Using RNA interference, we demonstrated that the chemotherapy induced
HB-EGF was largely
dependent on
activator protein-1 (AP-1) and NF-kappaB activation