Ebert et al., Immunity 2011
:
The distal V ( H ) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor dependent activity in pro-B cells
McManus et al., EMBO J 2011
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By binding to promoters and enhancers, Pax5 directly regulates the expression of multiple transcription factor , cell surface receptor and signal transducer genes