Gene interactions and pathways from curated databases and text-mining

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DAB2IP — KRAS

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: KRAS → DAB2IP (directlyDecreases, DAB2IP Activity, KRAS Activity) Wang et al., J Biol Chem 2002*
    Evidence: GST-DIP1/2 fusion protein containing the minimal Ras GAP domain (23), and either this fusion protein or GST protein was incubated with human recombinant [gamma -32P]GTP-bound Ha-Ras protein. The increasing amounts of GST-DIP1/2 (ranging from 0.2 to 1 µg) stimulated Ras GTPase activity in a dose-dependent manner