Gene interactions and pathways from curated databases and text-mining

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BCL10 — EPX

Text-mined interactions from Literome

Paiboonsukwong et al., Int J Hematol 2003 : Adding IFN-gamma or EPO induced Bcl-x expression in ECFCs, as determined by Western blotting, and expression was suppressed in the presence of Ly294002
Shen et al., Invest Ophthalmol Vis Sci 2010 : In contrast, EPO enhanced BAD phosphorylation and Bcl-xL expression but downregulated Bax
Xie et al., Eye (Lond) 2012 (Disease Models, Animal...) : Intravitreal injection of EPO 400 ng is safe, and EPO may suppress caspase-3 activation and enhance Bcl-X ( L ) expression, resulting in inhibition of apoptosis and protection of photoreceptor cells
Asano et al., J Toxicol Sci 2012 : These results showed a close association between reduced apoptotic cell death and increased mRNA levels of Bcl-xL and Mcl-1 in the presence of EPO