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Henry et al., Mol Cell Biol 2000
:
Ral activation of these responses is likely through an as yet uncharacterized effector pathway, as we find activation of NF-kappaB and the cyclin D1 promoter by Ral is independent of association of Ral with active phospholipase D1 or Ral binding protein 1, two proteins proposed to mediate Ral function in cells
Hu et al., Biochem Biophys Res Commun 2002
(Calcium Signaling) :
This study shows that activation of PLD by histamine regulates [ Ca ( 2+ ) ] ( i ) oscillation frequency and NF-kappaB activity in HAEC
Sethu et al., J Immunol 2008
(Calcium Signaling...) :
PLD1 is also required for NFkappaB and ERK1/2 activation in human monocytic cells