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MME — PTEN
Text-mined interactions from Literome
Osman et al., Cancer 2006
(Disease Progression...) :
The results indicated that the induction of
NEP expression inhibited established xenograft tumor growth, diminished Akt phosphorylation, and
increased PTEN protein levels
Karoor et al., Hypertension 2013
(Disease Models, Animal...) :
Loss of
NEP led to an increase in Src kinase activity and phosphorylation of
PTEN , resulting in activation of the platelet derived growth factor receptor ( PDGFR )
Abdulkareem et al., Niger Med J 2013
:
NEP can form a complex with PTEN and
enhance PTEN recruitment to the plasma membrane as well as stabilize its phosphatase activity