Gene interactions and pathways from curated databases and text-mining

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CD8B — IL5

Text-mined interactions from Literome

Braun et al., Eur J Immunol 2000 : In mixed lymphocyte cultures ( MLC ), the presence of CD8 ( + ) T cells in the responding cell population inhibited the secretion of IL-5
Willemsen et al., J Immunol 2006 (Melanoma) : The introduction of a mutated cysteine motif in CD8alpha, which prevents its binding to LCK and linker for activation of T cells, did not adversely affect expression and T cell cytotoxicity, but counteracted the CD8alpha mediated down-regulation of IL-4 and IL-5 , but not IL-10
Chaput et al., Gut 2009 (Adenocarcinoma...) : Finally, interleukin 6 and TGF beta 1 synergistically induced the generation of CD8 ( + ) CD25 ( + ) Foxp3 ( + ) T cells ex vivo
Ohnishi et al., J Allergy Clin Immunol 2009 (Inflammation...) : Adoptive transfer of U0126 treated CD8 ( + ) T cells into sensitized mice before secondary allergen challenge resulted in significant decreases in AHR, eosinophilic inflammation, goblet cell metaplasia, and IL-5 and IL-13 levels in bronchoalveolar lavage fluid of recipient mice
Ma et al., Scand J Immunol 2011 (Colonic Neoplasms) : This study aims to investigate the role of tumour derived Foxhead box P3 (Foxp3) ( + ) interleukin (IL)-17 ( + ) T cells on suppressing tumour-specific CD8 ( + ) T cells
Höllsberg et al., Proc Natl Acad Sci U S A 1995 : CD8 T-cell stimulation with the wild-type peptide antigen led to activation of p56lck kinase activity, interleukin 2 secretion, cytotoxicity, and clonal expansion