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Text-mined interactions from Literome
Tang et al., Mol Cancer Res 2006
(Breast Neoplasms...) :
Overexpression of
EMMPRIN in MDA-MB-231 breast cancer cells
stimulated the phosphorylation of only
Akt and MAPKs but not that of JUN and p38 kinases ... Conversely, inhibition of
EMMPRIN expression
resulted in suppressed
Akt and MAPK phosphorylation
Dai et al., Int J Cancer 2012
:
We found that KSHV activation of
emmprin induces
PI3K/Akt- and mitogen activated protein kinase ( MAPK ) -dependent secretion of vascular endothelial growth factor ( VEGF ) ... Functionally, EC invasion following de novo infection is induced by
emmprin dependent
PI3K/Akt and MAPK activation of VEGF