Gene interactions and pathways from curated databases and text-mining

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CXCL10 — HMOX1

Text-mined interactions from Literome

Datta et al., American journal of physiology. Renal physiology 2007 : Utilizing a CXCL-10 promoter luciferase construct, we observed that HO-1 induced CXCL-10 expression is regulated at the transcriptional level ... To evaluate the functional significance of HO-1 induced CXCL-10 release, we cultured human vascular endothelial cells in the absence and presence of culture supernatants of the HO-1 plasmid transfected RPTEC ... Thus HO-1 can regulate the expression of the anti-angiogenic CXCL-10 and may alter a critical balance between angiogenic vs. anti-angiogenic factors that are important to maintain renal microvasculature during injury
Liu et al., PloS one 2012 (Malaria) : ( 3 ) HO-1 transcription is positively regulated by CXCL10
Seidel et al., Eur Respir J 2013 : In human primary ASMCs, DMF inhibits CXCL10 secretion by reducing the cellular glutathione level and by activation of p38 MAPK and HO-1