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MMP2 — SERPINF1

Text-mined interactions from Literome

Chung et al., Gastroenterology 2009 (Fatty Liver) : Because matrix metalloproteinase (MMP)-2/9 activity regulates PEDF levels, we investigated whether PEDF degradation by MMPs has a permissive role in ethanol induced hepatic steatosis ... Ethanol exposed hepatic lysates degraded PEDF in a MMP-2/9 dependent manner, and liver sections demonstrated abundant MMP-2/9 activity in situ
Bandyopadhyay et al., Invest Ophthalmol Vis Sci 2012 (Retinal Neovascularization) : Inhibition of MMP-2/9 activity increased PEDF and decreased VEGF levels in the apical and basal supernatants but had no effect on their expression levels
Peng et al., PloS one 2012 (Nasopharyngeal Neoplasms...) : The expressions of vascular endothelial growth factor ( VEGF ), matrix metalloproteinase-2 (MMP-2), MMP-9 , and MMP-14 decreased, while the level of pigment epithelium derived factor (PEDF) increased
Alcantara et al., Cell Physiol Biochem 2013 (Neoplasm Metastasis...) : Regulation of MT1-MMP and MMP-2 by the Serpin PEDF : a Promising New Target for Metastatic Cancer ... Understanding the role of PEDF in the regulation of MT1-MMP and MMP-2 as it pertains to cancer control is important in order to understand whether and how such associations provide a novel target for cancer therapy