Gene interactions and pathways from curated databases and text-mining

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IL2 — PAX5

Text-mined interactions from Literome

Wallin et al., J Biol Chem 1999 : The levels of BSAP progressively decrease in response to IL-2 and this change correlates with the differentiation of B cells into antibody secreting plasma cells
Hsu et al., Proc Natl Acad Sci U S A 2006 : Expression of Pax5 , a B lymphoid affiliated transcription factor, is completely suppressed by enforced C/EBPalpha but not by ectopic IL-2 stimulation in proB cells
Rinkenberger et al., Immunity 1996 : Functional assays showed that BSAP mediates the silencing of the J chain gene during the early stages of B cell development, but repression is relieved during the antigen-driven stages in a concentration dependent manner by an IL-2 induced down-regulation of BSAP RNA expression