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IL2 — PAX5
Text-mined interactions from Literome
Wallin et al., J Biol Chem 1999
:
The levels of
BSAP progressively decrease in
response to
IL-2 and this change correlates with the differentiation of B cells into antibody secreting plasma cells
Hsu et al., Proc Natl Acad Sci U S A 2006
:
Expression of
Pax5 , a B lymphoid affiliated transcription factor, is completely
suppressed by enforced C/EBPalpha but not by ectopic
IL-2 stimulation in proB cells
Rinkenberger et al., Immunity 1996
:
Functional assays showed that BSAP mediates the silencing of the J chain gene during the early stages of B cell development, but repression is relieved during the antigen-driven stages in a concentration dependent manner by an
IL-2 induced down-regulation of
BSAP RNA expression