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FOXO1 — SETD2
Text-mined interactions from Literome
Alam et al., Endocrinology 2009
:
These results indicate that FSH stimulated
HIF-1 activation leading to up-regulation of targets such as vascular endothelial growth factor
requires not only PI3-kinase/AKT mediated activation of mammalian target of rapamycin as well as phosphorylation of
FOXO1 and possibly MDM2 but also a protein ( kinase ) activity that is inhibited by the classic ERK kinase inhibitor PD98059 but not ERK1/2 or 5
Kim et al., BMC cancer 2011
(Carcinoma...) :
In addition, cell culture experiments showed that
FOXO1 suppression
increased the mRNA and protein expressions of
HIF-1a