Gene interactions and pathways from curated databases and text-mining

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SDC2 — TNF

Text-mined interactions from Literome

Sebestyén et al., Cytokine 2000 : In the present work the regulatory effect of IL-1beta, IL-6, TNF-alpha , IFN-gamma and TGF-beta1 on syndecan-1 and syndecan-2 expression of hepatocytes, hepatoma cell lines, liver and skin fibroblasts has been studied
Bussini et al., Immunity & ageing : I & A 2005 : HSPG stimulated up-regulation of tumor necrosis factor-alpha (TNF-alpha) , production of inducible nitric oxide synthase (iNOS) mRNA and accumulation of TNF-alpha protein and nitrite ( NO2- ) in a time- and concentration dependent manner
Teixé et al., Mol Immunol 2008 : However, cross linking of cell bound syndecan-2 or syndecan-4 via immobilized antibodies blocked proliferation and decreased TNF production of T cells in the presence of optimal levels of anti-CD3