Gene interactions and pathways from curated databases and text-mining

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CD40LG — IL15

Text-mined interactions from Literome

Skov et al., J Immunol 2000 : IL-2 and IL-15 regulate CD154 expression on activated CD4 T cells
Liu et al., J Immunol 2000 (Inflammatory Bowel Diseases) : This capacity of LP-T cells was strongly enhanced by preincubation in IL-15 and was the result of higher CD40L expression after culture in IL-15
Sugiura et al., J Immunol 2000 (Dermatomyositis...) : Increased CD40 expression on muscle cells of polymyositis and dermatomyositis : role of CD40-CD40 ligand interaction in IL-6, IL-8, IL-15 , and monocyte chemoattractant protein-1 production ... Recombinant human CD40L markedly increased the production of IL-6, IL-8, IL-15 , and monocyte chemoattractant protein-1 of SkMC 2859
Möttönen et al., Immunology 2000 (Arthritis, Rheumatoid) : As interleukin (IL)-15 is a potent activator of synovial T cells we wanted to study whether IL-15 also regulated the expression of CD154 on these T cells ... IL-15 significantly increased the expression of CD154 on SF and PB T cells from patients, whereas IL-2 had minimal effects ... Our results show that SF T cells up-regulate the expression of CD154 in the presence of IL-15 , a cytokine present in the synovium of patients with RA
McDowell et al., Infect Immun 2002 : Leishmania priming of human dendritic cells for CD40 ligand induced interleukin-12p70 secretion is strain and species dependent
Möttönen et al., Arthritis Res 2002 (Arthritis, Rheumatoid) : Regulation of CD154 induced interleukin-12 production in synovial fluid macrophages
Wagner et al., Arterioscler Thromb Vasc Biol 2002 : One consequence of this statin dependent downregulation of CD40 expression was a decrease in CD40 ligand induced endothelial interleukin-12 expression
Wang et al., Clin Exp Immunol 2003 (Arthritis, Rheumatoid) : CD40L expression on synovial CD4+ T cells was increased greatly in CCR5+ portions by IL-15
Lin et al., Biol Neonate 2004 : Both IL-7 and IL-15 could augment the P+I induced CD40L expression on CB CD4+/CD45RA+ T cells ... However, the enhancing effect of IL-15 on CB CD40L/CD45RA expression was more sustained than that of IL-7
Loskog et al., Clin Cancer Res 2005 (Carcinoma...) : CD40L stimulation of dendritic cells induces interleukin-12 expression that drives Th1 type of immune responses with activation of cytotoxic T cells
Bose et al., Hum Immunol 2007 (Carcinoma, Squamous Cell...) : Natural killer cell mediated cytotoxicity of tumor cells initiated by neem leaf preparation is associated with CD40-CD40L mediated endogenous production of interleukin-12
Schneider et al., J Immunol 2011 (Multiple Sclerosis) : We established that CD40L activation of B cells from healthy donors increased their IL-15 levels, reaching those of MS patients
Kennedy et al., Eur J Immunol 1996 : CD40/CD40 ligand interactions are required for T cell dependent production of interleukin-12 by mouse macrophages