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CAPS2 — NTF3

Text-mined interactions from Literome

Sadakata et al., J Neurosci 2004 : The secretory granule associated protein CAPS2 regulates neurotrophin release and cell survival ... Thus, we suggest that CAPS2 mediates the depolarization dependent release of NT-3 and BDNF from granule cells, leading to regulation in cell differentiation and survival during cerebellar development
Sadakata et al., J Histochem Cytochem 2007 : CAPS1 regulates catecholamine release from neuroendocrine cells, whereas CAPS2 is involved in the release of brain derived neurotrophic factor and neurotrophin-3 from cerebellar granule cells
Sadakata et al., Neurosci Res 2010 (Genetic Predisposition to Disease) : We found that CAPS2 is involved in the secretion of brain derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) and that CAPS2 KO mice not only have deficits in neuronal development and survival but also exhibit abnormal behaviors, including impaired social interaction, hyperactivity, an abnormal sleep-wake rhythm and increased anxiety in unfamiliar environments