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RAC1 — SCARB1

Text-mined interactions from Literome

Hullinger et al., J Biol Chem 2001 : Cotransfection of PAK1 constructs containing mutations in both the kinase domain and the Cdc42/Rac binding domain attenuated the PAK1 mediated down-regulation of the promoter, suggesting that Rac and Cdc42 are required for PAK1 mediated decreases in SR-BI promoter activity
Osada et al., J Biochem 2009 (MAP Kinase Signaling System) : These results collectively suggested the following signalling pathway for the SR-BI induced phagocytosis : ( i ) PS-recognizing SR-BI activates associated GULP ; ( ii ) activated GULP induces MAPK phosphorylation ; ( iii ) activated MAPK increases GTP bound Rac1 ; and ( iv ) activated Rac1 induces a rearrangement of the actin cytoskeleton