Xin et al., PloS one 2010
(Stroke) :
Collectively, these in vivo and in vitro data suggest that the MSC mediated increased activation of tPA in astrocytes promotes neurite outgrowth after stroke
Xin et al., J Cereb Blood Flow Metab 2011
(Stroke) :
To probe the mechanisms that underlie MSC mediated activation of tPA , we investigated the morphogenetic gene, sonic hedgehog (Shh) pathway