Park et al., J Biol Chem 2006
:
TGFbeta(1) also mediates a decrease in GTP bound RhoA and a reciprocal increase in the expression of the RhoA GTPase activating protein , p190RhoGAP, whereas total RhoA is unchanged
Fukuda et al., Hepatology 1998
(Carcinoma, Hepatocellular...) :
TGF-beta1 induced tyrosine dephosphorylation of Ras guanosine triphosphatase activating protein ( Ras-GAP ) and Ras inactivation in HepG2 cells, but induced Ras-GAP phosphorylation and Ras activation in Mahlavu cells