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CD46 — EPHB2

Text-mined interactions from Literome

Wong et al., Allergy 2006 : Using various selective inhibitors for signaling molecules, we found that the inductions of IL-8, MCP-1 , and I-309 were mediated by either SCF activated ERK or TNF-alpha activated p38 MAPK, while the induction of IP-10 by TNF-alpha was mediated by both activated p38 MAPK and NF-kappaB
Nakazawa et al., Invest Ophthalmol Vis Sci 2007 (Disease Models, Animal...) : RD-induced reactive gliosis, characterized by GFAP and vimentin upregulation, Erk and c-fos activation, MCP-1 induction , and increased monocyte recruitment in WT mice
González-Navarro et al., Arterioscler Thromb Vasc Biol 2008 (Atherosclerosis...) : Inhibition of AKT or ERK1/2 , a downstream target of RAS, upregulates Mcp1 in VSMCs
Majkova et al., Toxicol Appl Pharmacol 2009 (Atherosclerosis...) : Also, MCP-1 up-regulation by PCB77 was prevented by inhibiting p38 and c-Jun N-terminal kinase (JNK), but not ERK1/2 , suggesting regulatory functions via p38 and JNK MAPK pathways
Cicha et al., J Atheroscler Thromb 2011 : In resveratrol treated monocytic cells, MCP-1 induced Erk phosphorylation downstream of CCR2 receptor was dose-dependently inhibited, as observed by Western blot analysis