Gene interactions and pathways from curated databases and text-mining

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BAD — TGFB1

Text-mined interactions from Literome

Kim et al., Mol Cell Biol 2002 (Carcinoma, Hepatocellular...) : Transforming growth factor beta 1 induces apoptosis through cleavage of BAD in a Smad3 dependent mechanism in FaO hepatoma cells ... However, TGF-beta 1 induced caspase dependent cleavage of BAD at its N terminus to generate a 15-kDa truncated protein ... These results suggest that TGF-beta 1 induces apoptosis through the cleavage of BAD in a Smad3 dependent mechanism
Wang et al., Carcinogenesis 2005 : PD98059 also prevented the inhibitory effect of RON on TGF-beta1 induced cleavage of caspase-3 and BAD