◀ Back to TGFB1
RNF19A — TGFB1
Text-mined interactions from Literome
Kucich et al., Arch Biochem Biophys 2000
:
TGF-beta1 stimulation of fibronectin transcription in cultured human lung fibroblasts
requires active geranylgeranyl transferase I, phosphatidylcholine-specific phospholipase C, protein kinase C-delta, and
p38 , but not erk1/erk2
Gruden et al., Diabetes 2000
:
At 33 h,
TGF-beta1 blockade did not affect stretch induced fibronectin production, but partially
prevented stretch induced
p38 MAP kinase activation ( 59 % inhibition, P < 0.05 )
Weigert et al., J Am Soc Nephrol 2000
(Hyperglycemia) :
The high glucose induced
TGF-beta1 promoter activation was also
prevented by inhibitors of protein kinase C and
p38 mitogen activated proteinkinase
Chin et al., American journal of physiology. Renal physiology 2001
:
TGF-beta(1) rapidly
induced p38 MAPK phosphorylation in wild-type and empty vector ( pcDNA3 ) -transfected control mesangial cells ... Interestingly, transfection with dominant negative TbetaR-II ( M ) failed to block
TGF-beta(1) induced
p38 MAPK phosphorylation
Bhowmick et al., J Biol Chem 2001
:
Integrin beta 1 signaling is necessary for
transforming growth factor-beta activation of
p38MAPK and epithelial plasticity
Goldberg et al., Am J Physiol Lung Cell Mol Physiol 2002
:
p38 MAPK
activation by
TGF-beta1 increases MLC phosphorylation and endothelial monolayer permeability
Verma et al., J Biol Chem 2002
:
Activation of the
p38 mitogen activated protein kinase
mediates the suppressive effects of type I interferons and
transforming growth factor-beta on normal hematopoiesis
Rodríguez-Barbero et al., FEBS Lett 2002
:
These data indicate that
TGF-beta1 induced
p38 activation is involved in TGF-beta1 stimulated collagen synthesis
Park et al., Hepatology 2002
(Carcinoma, Hepatocellular...) :
In addition, antiapoptotic Bcl-2 blocked mitochondrial cytochrome c release, suppressing
TGF-beta1 induced activation of JNK and
p38
Hyman et al., Surgery 2002
(MAP Kinase Signaling System) :
We hypothesized that
TGF-beta1 activates endothelial cell MAPKs and
induces apoptosis through
p38 ( MAPK ) activation ...
TGF-beta1 induces endothelial cell apoptosis through
p38 ( MAPK ) activation
Edlund et al., Mol Biol Cell 2003
(Prostatic Neoplasms) :
Ectopic expression of wild-type TAK1 promoted
TGF-beta1 induced phosphorylation of
p38 and apoptosis, whereas dominant negative TAK1 reduced TGF-beta1 induced phosphorylation of p38 and apoptosis
Roy et al., Circ Res 2003
(Hyperoxia) :
The molecular signature response to perceived hyperoxia included ( 1 ) induction of p21, cyclin D1, cyclin D2, cyclin G1, Fos related antigen-2, and
transforming growth factor-beta1 , ( 2 ) lowered telomerase activity, and ( 3 )
activation of transforming growth factor-beta1 and
p38 mitogen activated protein kinase
Utsugi et al., Am J Respir Cell Mol Biol 2003
:
PI3K inhibitors dose-dependently suppressed
TGF-beta1 induced JNK, but not
p38 MAP kinase activation
Lechuga et al., Am J Physiol Gastrointest Liver Physiol 2004
:
Our results also show that this
TGF-beta1 mediated effect is de novo protein synthesis dependent and requires the activity of
p38MAPK , phosphatidylinositol 3-kinase, AKT, and p70 ( S6k )
Fang et al., J Cell Biochem 2005
:
Nicotine treatment down-regulated
TGF-beta1 induced
p38 MAPK phosphorylation
Hu et al., Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 2005
:
( 2 )
TGF-beta1 induced
p38 , Erk kinase phosphorylation but not JNK kinase
Sohn et al., Am J Physiol Heart Circ Physiol 2006
:
Inhibition of
p38 ( mapk ) activities did not
affect LDL induced
TGF-beta1 , CTGF, and collagen IV expression
Lu et al., J Appl Physiol 2006
:
Knockdown of Smad2 protein prevented
TGF-beta1 induced
p38 activation and endothelial barrier dysfunction
García-Alvarez et al., Exp Lung Res 2006
(Pulmonary Fibrosis) :
TGF-beta1 induced the phosphorylation of
p38 and extracellular signal regulated kinase ( ERK ) 1/2
Yongchaitrakul et al., Eur J Oral Sci 2007
(MAP Kinase Signaling System) :
Analyses by reverse transcription-polymerase chain reaction ( RT-PCR ) and enzyme linked immunosorbent assay ( ELISA ) revealed that
TGF-beta1 ( 1 ng ml(-1) )
induced NGF mRNA and protein expression through the phosphorylation of
p38 mitogen activated protein kinase ( MAPK ) and c-Jun N-terminal kinase (JNK)
Yoshikawa et al., Eur J Pharmacol 2010
(MAP Kinase Signaling System) :
TSA prevented TGF-beta1 induced apoptosis and the activation of caspase-8 and caspase-9 in RPTECs but did not inhibit the
TGF-beta1 induced phosphorylation of Smad3 and
p38 mitogen activated protein kinase ( MAPK )
Wei et al., Cell Biol Int 2013
:
Our present study is to explore the role of AEG-1 in
TGF-beta1 induced
p38 MAPK activation and EMT process in human renal tubular epithelial ( HK-2 ) cells