Gene interactions and pathways from curated databases and text-mining

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RNF19A — TGFB1

Text-mined interactions from Literome

Kucich et al., Arch Biochem Biophys 2000 : TGF-beta1 stimulation of fibronectin transcription in cultured human lung fibroblasts requires active geranylgeranyl transferase I, phosphatidylcholine-specific phospholipase C, protein kinase C-delta, and p38 , but not erk1/erk2
Gruden et al., Diabetes 2000 : At 33 h, TGF-beta1 blockade did not affect stretch induced fibronectin production, but partially prevented stretch induced p38 MAP kinase activation ( 59 % inhibition, P < 0.05 )
Weigert et al., J Am Soc Nephrol 2000 (Hyperglycemia) : The high glucose induced TGF-beta1 promoter activation was also prevented by inhibitors of protein kinase C and p38 mitogen activated proteinkinase
Chin et al., American journal of physiology. Renal physiology 2001 : TGF-beta(1) rapidly induced p38 MAPK phosphorylation in wild-type and empty vector ( pcDNA3 ) -transfected control mesangial cells ... Interestingly, transfection with dominant negative TbetaR-II ( M ) failed to block TGF-beta(1) induced p38 MAPK phosphorylation
Bhowmick et al., J Biol Chem 2001 : Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity
Goldberg et al., Am J Physiol Lung Cell Mol Physiol 2002 : p38 MAPK activation by TGF-beta1 increases MLC phosphorylation and endothelial monolayer permeability
Verma et al., J Biol Chem 2002 : Activation of the p38 mitogen activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-beta on normal hematopoiesis
Rodríguez-Barbero et al., FEBS Lett 2002 : These data indicate that TGF-beta1 induced p38 activation is involved in TGF-beta1 stimulated collagen synthesis
Park et al., Hepatology 2002 (Carcinoma, Hepatocellular...) : In addition, antiapoptotic Bcl-2 blocked mitochondrial cytochrome c release, suppressing TGF-beta1 induced activation of JNK and p38
Hyman et al., Surgery 2002 (MAP Kinase Signaling System) : We hypothesized that TGF-beta1 activates endothelial cell MAPKs and induces apoptosis through p38 ( MAPK ) activation ... TGF-beta1 induces endothelial cell apoptosis through p38 ( MAPK ) activation
Edlund et al., Mol Biol Cell 2003 (Prostatic Neoplasms) : Ectopic expression of wild-type TAK1 promoted TGF-beta1 induced phosphorylation of p38 and apoptosis, whereas dominant negative TAK1 reduced TGF-beta1 induced phosphorylation of p38 and apoptosis
Roy et al., Circ Res 2003 (Hyperoxia) : The molecular signature response to perceived hyperoxia included ( 1 ) induction of p21, cyclin D1, cyclin D2, cyclin G1, Fos related antigen-2, and transforming growth factor-beta1 , ( 2 ) lowered telomerase activity, and ( 3 ) activation of transforming growth factor-beta1 and p38 mitogen activated protein kinase
Utsugi et al., Am J Respir Cell Mol Biol 2003 : PI3K inhibitors dose-dependently suppressed TGF-beta1 induced JNK, but not p38 MAP kinase activation
Lechuga et al., Am J Physiol Gastrointest Liver Physiol 2004 : Our results also show that this TGF-beta1 mediated effect is de novo protein synthesis dependent and requires the activity of p38MAPK , phosphatidylinositol 3-kinase, AKT, and p70 ( S6k )
Fang et al., J Cell Biochem 2005 : Nicotine treatment down-regulated TGF-beta1 induced p38 MAPK phosphorylation
Hu et al., Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 2005 : ( 2 ) TGF-beta1 induced p38 , Erk kinase phosphorylation but not JNK kinase
Sohn et al., Am J Physiol Heart Circ Physiol 2006 : Inhibition of p38 ( mapk ) activities did not affect LDL induced TGF-beta1 , CTGF, and collagen IV expression
Lu et al., J Appl Physiol 2006 : Knockdown of Smad2 protein prevented TGF-beta1 induced p38 activation and endothelial barrier dysfunction
García-Alvarez et al., Exp Lung Res 2006 (Pulmonary Fibrosis) : TGF-beta1 induced the phosphorylation of p38 and extracellular signal regulated kinase ( ERK ) 1/2
Yongchaitrakul et al., Eur J Oral Sci 2007 (MAP Kinase Signaling System) : Analyses by reverse transcription-polymerase chain reaction ( RT-PCR ) and enzyme linked immunosorbent assay ( ELISA ) revealed that TGF-beta1 ( 1 ng ml(-1) ) induced NGF mRNA and protein expression through the phosphorylation of p38 mitogen activated protein kinase ( MAPK ) and c-Jun N-terminal kinase (JNK)
Yoshikawa et al., Eur J Pharmacol 2010 (MAP Kinase Signaling System) : TSA prevented TGF-beta1 induced apoptosis and the activation of caspase-8 and caspase-9 in RPTECs but did not inhibit the TGF-beta1 induced phosphorylation of Smad3 and p38 mitogen activated protein kinase ( MAPK )
Wei et al., Cell Biol Int 2013 : Our present study is to explore the role of AEG-1 in TGF-beta1 induced p38 MAPK activation and EMT process in human renal tubular epithelial ( HK-2 ) cells