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BDNF — S100A12

Text-mined interactions from Literome

Buldyrev et al., J Neurochem 2006 (Calcium Signaling...) : Using ELISA in situ, we show that CGRP ( 1-1000 nM ) potently enhances BDNF release from cultured trigeminal neurons ... Intriguingly, CGRP mediated BDNF release, unlike BDNF release evoked by physiological patterns of electrical stimulation, is independent of extracellular calcium ... Depletion of intracellular calcium stores with thapsigargin blocks the CGRP mediated BDNF release
Bałkowiec-Iskra et al., Neuroscience 2011 (Inflammation) : TNFa increases the phosphorylated form of the cyclic AMP-responsive element binding protein ( CREB ), a transcription factor involved in regulation of BDNF expression in neurons, and activates transcription of BDNF exon IV ( former exon III ) and, to a lesser extent, exon VI ( former exon IV ), but not exon I. TNFa mediated increase in BDNF expression is accompanied by increase in calcitonin gene related peptide (CGRP) , which is consistent with previously published studies, and indicates that both peptides are similarly regulated in TG neurons by inflammatory mediators
Piehl et al., Eur J Neurosci 1995 : BDNF , on the other hand increased alpha-CGRP and decreased beta-CGRP mRNA levels, though these effects were moderate compared with the effects of FGF-5