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CDH17 — EGF
Text-mined interactions from Literome
Smith et al., American journal of physiology. Renal physiology 2009
:
Quantitative RT-PCR and a luciferase reporter assay suggested that
sHB-EGF repressed transcription of
E-cadherin , and a concomitant TGF-beta independent upregulation of the E-cadherin repressor Snail-2 was observed
Cheng et al., Oncogene 2013
(Ovarian Neoplasms) :
These two signaling pathways contribute to the
EGF induced downregulation of
E-cadherin , which subsequently increases the invasive capability of ovarian cancer cells
Cheng et al., J Clin Endocrinol Metab 2012
:
Moreover, the inhibition of EGF induced ERK1/2, p38, and Akt activation by pharmacological inhibitors attenuated
EGF induced Slug expression and the down-regulation of
E-cadherin , as well as subsequent cell invasion
Sakamoto et al., Cancer Sci 2012
(Stomach Neoplasms) :
Expression of
LI-cadherin was
induced by both
EGF and TGF-a, as detected by quantitative RT-PCR and Western blot analysis ... A luciferase assay showed that
LI-cadherin promoter activity was
enhanced by
EGF or TGF-a in both HT-29 cells and MKN-74 GC cells