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EDAR — NFKB1
Text-mined interactions from Literome
Koppinen et al., Exp Cell Res 2001
:
When
Edar was expressed at low levels, the
NF-kappaB response was
enhanced by coexpression of ectodysplasin
Shindo et al., Biochem Biophys Res Commun 2004
(Ectodermal Dysplasia) :
While IKK1/IKKalpha and IKK2/IKKbeta are required for
EDAR induced
NF-kappaB activation, they are dispensable for its ability to repress Lef-1/beta-catenin dependent transcription ... In contrast, NIK is not involved in
EDAR induced
NF-kappaB activation or Lef-1/beta-catenin transcriptional repression
Morlon et al., Hum Mol Genet 2005
(Ectodermal Dysplasia) :
TAB2, TRAF6 and TAK1 are involved in
NF-kappaB activation
induced by the TNF-receptor,
Edar and its adaptator Edaradd
Chassaing et al., Br J Dermatol 2010
(Ectodermal Dysplasia...) :
EDARADD interacts with the TAB2/TRAF6/TAK1 complex, which is necessary for
NF-kappaB activation by
EDAR