Gene interactions and pathways from curated databases and text-mining

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ROCK1 — SMAD3

Text-mined interactions from Literome

Rodrigues Díez et al., PloS one 2010 (Fibrosis) : In cultured rat VSMCs, direct AngII/Smad pathway activation was mediated by p38 MAPK and ROCK activation
Wang et al., J Cell Mol Med 2012 (Fibrosis) : In contrast, treatment with Y-27632 or SB-431542, respectively suppressed ROCK dependent PKC-d and Smad3 activation, but BMP-2 was only up-regulated by Y-27632