Gene interactions and pathways from curated databases and text-mining
IL8: top 25 interacting genes
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IL8-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IL8, not among the Top 25
Other genes interacting with IL8. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

TLR4 ▸ TLR2 ▸ FOS ▸ IL4 ▸ IL2 ▸ CSF2 ▸ IL17A ▸
TLR3 ▸ ICAM1 ▸ NM ▸ TLR5 ▸ PTGS2 ▸ CD40 ▸ IL13 ▸
VEGFA ▸ AHSA1 ▸ TLR9 ▸ TLR1 ▸ CA2 ▸ CCL2 ▸ TLR8 ▸
IL3 ▸ TLR7 ▸ IL15 ▸ TLR6 ▸ RNF19A ▸ LTA ▸ TLR10 ▸
IL5 ▸ TGFB1 ▸ IL33 ▸ TCF21 ▸ TCF4 ▸ F2RL1 ▸ NOS2 ▸
IL18 ▸ TCF23 ▸ IL22 ▸ TCF19 ▸ TCF7 ▸ TCF15 ▸ TCF25 ▸
TCF20 ▸ TCF24 ▸ TCF3 ▸ TCF12 ▸ CRK ▸ NA ▸ PIK3R1 ▸
CSE ▸ PIK3CA ▸ NFKBIA ▸ IL32 ▸ IL1RN ▸ MMP9 ▸ LPA ▸
PAF1 ▸ LEO1 ▸ EGF ▸ HGF ▸ CDC73 ▸ IL31 ▸ GRAP2 ▸
CTR9 ▸ WDR61 ▸ APOB ▸ IFNB1 ▸ IL7 ▸ IL11 ▸ S100A8 ▸
CXCR1 ▸ MMP2 ▸ ITGAM ▸ IL19 ▸ IL20 ▸ IL16 ▸ FGF2 ▸
IL25 ▸ IL21 ▸ IL9 ▸ MMP3 ▸ INS ▸ IL24 ▸ SAA1 ▸
IL34 ▸ FAS ▸ POLDIP2 ▸ IL37 ▸ IL27 ▸ IL26 ▸ MIF ▸
NOS1 ▸ EGFR ▸ PI3 ▸ CXCR2 ▸ ALB ▸ CRP ▸ AKT3 ▸
AKT1 ▸ AKT2 ▸ CASP3 ▸ CALM3 ▸ MMP1 ▸ MMP13 ▸ NOX1 ▸
CD14 ▸ IKBKB ▸ CASP4 ▸ F2R ▸ CASP7 ▸ CASP5 ▸ NOS3 ▸
CASP1 ▸ CASP6 ▸ CASP14 ▸ CASP9 ▸ CASP8 ▸ CASP12 ▸ CASP10 ▸
CASP16 ▸ CASP2 ▸ NOX4 ▸ CD40LG ▸ PTX3 ▸ NOX5 ▸ HMGB1 ▸
PLG ▸ NOX3 ▸ TGFB2 ▸ ITGB2 ▸ MYLIP ▸ IGF1 ▸ PTK7 ▸
LIF ▸ PTK2 ▸ TNFSF10 ▸ SELE ▸ CHUK ▸ PTK6 ▸ NOD1 ▸
MYD88 ▸ GP5 ▸ PRG2 ▸ SRC ▸ MUC1 ▸ GP6 ▸ GP9 ▸
ERVK-6 ▸ IKBKG ▸ IL12B ▸ GP2 ▸ PRG4 ▸ PRG3 ▸ STAT3 ▸
MMP8 ▸ IFNA2 ▸ MAP3K7 ▸ CXCL12 ▸ TREM1 ▸ PTX4 ▸ LEP ▸
IFNA10 ▸ PRKAR1A ▸ HNRNPH1 ▸ SERPINE1 ▸ PRKACG ▸ IFNA16 ▸ VCAM1 ▸
LTB ▸ IFNA17 ▸ IFNA21 ▸ CRH ▸ HNRNPF ▸ IFNA7 ▸ IFNA6 ▸
MPO ▸ PRKAR1B ▸ IFNA13 ▸ PLD2 ▸ PTBP1 ▸ IFNA4 ▸ IFNA14 ▸
SOD3 ▸ PRKAR2A ▸ PAM ▸ VIP ▸ HDAC2 ▸ SOD1 ▸ SOD2 ▸
IFNA5 ▸ PRKAR2B ▸ PTBP2 ▸ CSF3 ▸ MMP7 ▸ WNK1 ▸ IL12A ▸
S100A12 ▸ PRKACB ▸ IFNA1 ▸ IFNA8 ▸ MMP14 ▸ MMP12 ▸ MMP20 ▸
EGR1 ▸ NOD2 ▸ CAT ▸ MMP10 ▸ PLD1 ▸ MMP25 ▸ IL1R1 ▸
FGF1 ▸ SETD2 ▸ TNFRSF1A ▸ TGFB3 ▸ ELANE ▸ MMP26 ▸ CSK ▸
EDN1 ▸ CXCL10 ▸ MMP27 ▸ MMP21 ▸ MSH3 ▸ MMP16 ▸ MMP17 ▸
CCL3 ▸ MMP28 ▸ MMP15 ▸ HDAC1 ▸ MMP24 ▸ MMP11 ▸ SPP1 ▸
MMP19 ▸ ANGPT2 ▸ CD4 ▸ NAALADL1 ▸ MSH6 ▸ MSH4 ▸ TAB1 ▸
MSH5 ▸ MAP2K1 ▸ FGF7 ▸ MSH2 ▸ TRAF6 ▸ PLD4 ▸ PLA2G1B ▸
PLD3 ▸ SST ▸ CD8A ▸ QRICH2 ▸ PLD5 ▸ SYT1 ▸ AHR ▸
PLD6 ▸ QRICH1 ▸ FASLG ▸ FGF19 ▸ FGF20 ▸ HMOX1 ▸ PDLIM7 ▸
FGF22 ▸ TXN ▸ STX2 ▸ RAC1 ▸ CD46 ▸ C1QA ▸ FGF21 ▸
FGF10 ▸ FGF17 ▸ FGF5 ▸ SOCS3 ▸ ITGB1 ▸ CD28 ▸ P2RY6 ▸
ADIPOQ ▸ FGF12 ▸ FGF18 ▸ FGF14 ▸ CSF1 ▸ LTF ▸ ETS1 ▸
CSRP1 ▸ FGF9 ▸ SAA2 ▸ HSPD1 ▸ CD38 ▸ FGF23 ▸ FGF16 ▸
HDAC3 ▸ TNFSF12 ▸ HDAC6 ▸ FGF11 ▸ PPARG ▸ FGF3 ▸ CXCL1 ▸
NGF ▸ FGF8 ▸ STAT1 ▸ SELL ▸ FGF13 ▸ HDAC5 ▸ FGF4 ▸
C1QB ▸ SELP ▸ FGF6 ▸ MUC19 ▸ ECM1 ▸ MUC2 ▸ PF4 ▸
RHO ▸ RBBP7 ▸ ANG ▸ MUC6 ▸ IL2RA ▸ SETBP1 ▸ AGTR2 ▸
PLAU ▸ CD8B ▸ SAA4 ▸ ANGPT1 ▸ TRPV1 ▸ MUC12 ▸ HDAC11 ▸
CPOX ▸ ECM2 ▸ PDCD11 ▸ STAT4 ▸ MUC13 ▸ MUC16 ▸ GPI ▸
NAP1L4 ▸ BCL3 ▸ MUC4 ▸ PRTN3 ▸ PLA2G4A ▸ MUC20 ▸ HDAC4 ▸
ITIH4 ▸ ST8SIA2 ▸ HSPG2 ▸ PPARA ▸ MUC22 ▸ MUC8 ▸ CD79A ▸
APC ▸ RBBP4 ▸ MUC15 ▸ RHOA ▸ HDAC10 ▸ HSPB1 ▸ HES1 ▸
CR1 ▸ CXCR4 ▸ CXCR3 ▸ HDAC9 ▸ NPS ▸ CFTR ▸ HDAC8 ▸
MUC17 ▸ MUC7 ▸ MTOR ▸ TAT ▸ CISH ▸ STX1A ▸ MTX1 ▸
PRKCD ▸ HDAC7 ▸ MUC21 ▸ PDGFB ▸ TNMD ▸ TNFSF13B ▸ OSM ▸
RNASE3 ▸ HDC ▸ CHI3L1 ▸ ICAM3 ▸ UTP3 ▸ SMAD3 ▸ PAEP ▸
PRKAB2 ▸ TF ▸ TAC1 ▸ TAC3 ▸ PRR19 ▸ PRR3 ▸ PRKAG1 ▸
A2M ▸ PRL ▸ PRR9 ▸ IL1R2 ▸ IRAK3 ▸ NR0B1 ▸ ELF3 ▸
PRR4 ▸ PTAFR ▸ ADCYAP1 ▸ TP53 ▸ ICOSLG ▸ APEX1 ▸ ESR1 ▸
BRAF ▸ HES2 ▸ IBD4 ▸ FGG ▸ MT4 ▸ AZU1 ▸ PGD ▸
PRR16 ▸ SEA ▸ MUC5AC ▸ CXCL17 ▸ CXCL6 ▸ PRR22 ▸ CXCL9 ▸
HES7 ▸ ADAM17 ▸ CALM2 ▸ FCGR1A ▸ PRR25 ▸ FGA ▸ IBD3 ▸
CALM1 ▸ MET ▸ IFI44 ▸ MAP2K7 ▸ MPL ▸ BCL2 ▸ HES5 ▸
PRKAG2 ▸ UTP18 ▸ UTP6 ▸ HES4 ▸ ICAM2 ▸ EPO ▸ PRR26 ▸
DDIT3 ▸ LPL ▸ HBEGF ▸ HES3 ▸ PKD1 ▸ CXCL11 ▸ ELF4 ▸
PRR15 ▸ CYP1A1 ▸ UTP20 ▸ PRR24 ▸ NR4A2 ▸ IBD9 ▸ FOXO3 ▸
PGF ▸ ICAM4 ▸ ADAM11 ▸ DUSP1 ▸ SIGLEC7 ▸ PRR7 ▸ UTP15 ▸
ICAM5 ▸ IL17F ▸ PRR11 ▸ PRR5 ▸ PRKAA1 ▸ NUP43 ▸ SELPLG ▸
IBD7 ▸ PRKCA ▸ EMD ▸ JAK2 ▸ ETS2 ▸ PRDX2 ▸ TAC4 ▸
IBD2 ▸ TGFA ▸ PRR13 ▸ TFPI ▸ RELB ▸ GRP ▸ MAP3K1 ▸
IRAK1 ▸ DEFA1 ▸ ARG1 ▸ IBD6 ▸ PRR14 ▸ CCR5 ▸ CTNNB1 ▸
PRR21 ▸ ROCK2 ▸ MT3 ▸ UTP23 ▸ TPO ▸ RENBP ▸ PRR18 ▸
PRKAA2 ▸ IBD5 ▸ HES6 ▸ BCL10 ▸ PRKAB1 ▸ IBD8 ▸ PRR12 ▸
ARG2 ▸ NTS ▸ CCL20 ▸ CXCL14 ▸ FUT4 ▸ BCL6 ▸ GRB14 ▸
TNFRSF1B ▸ KRT10 ▸ WNT2 ▸ CX3CL1 ▸ CEACAM1 ▸ FUT11 ▸ ROCK1 ▸
HMGB4 ▸ IL23A ▸ HCG26 ▸ CXCR6 ▸ CNR2 ▸ KLK3 ▸ FUT1 ▸
ELF1 ▸ TNFRSF9 ▸ CAPN14 ▸ RNASE2 ▸ HCG8 ▸ REL ▸ RETN ▸
CSTA ▸ MEPE ▸ RAG1 ▸ FOSL1 ▸ HRH1 ▸ DDX58 ▸ SMAD1 ▸
ADM ▸ HIF1A ▸ CXCL16 ▸ PARK7 ▸ HCG27 ▸ TRNAI1 ▸ APOA2 ▸
DEFA1B ▸ HLA-DRB1 ▸ SPESP1 ▸ GSTM1 ▸ FOXO6 ▸ NPY6R ▸ ALX1 ▸
HCG23 ▸ TEC ▸ SMAD9 ▸ ALX3 ▸ MRXS5 ▸ PINK1 ▸ GAST ▸
KLRB1 ▸ MYO10 ▸ MAP2K2 ▸ TNPO1 ▸ CAPN8 ▸ ARSA ▸ SFXN1 ▸
SERPINE2 ▸ HCG14 ▸ MYO19 ▸ ACKR3 ▸ ABL1 ▸ CTSS ▸ PDCD4 ▸
PTPN11 ▸ CEBPB ▸ CTSB ▸ APOA1 ▸ RAC3 ▸ CYP1A2 ▸ IGF2 ▸
WNT4 ▸ PAH ▸ DPM3 ▸ FGFR2 ▸ ASIP ▸ HCG9 ▸ TRAF2 ▸
CD1D ▸ CAPN3 ▸ CGN ▸ MYO6 ▸ SYK ▸ STAT5A ▸ CAPN10 ▸
GH1 ▸ CXCL5 ▸ CD2 ▸ GRB2 ▸ GHRH ▸ AREG ▸ AR ▸
WNT6 ▸ CAPN7 ▸ MKNK1 ▸ UCN2 ▸ CAPN15 ▸ HCG25 ▸ GRB10 ▸
VCP ▸ WNT11 ▸ CXCL3 ▸ CD163 ▸ FOXO4 ▸ CA1 ▸ NPY ▸
BLM ▸ RAC2 ▸ C3 ▸ POU2F1 ▸ FUT6 ▸ PAK7 ▸ THBD ▸
WNT3 ▸ WNT1 ▸ CNR1 ▸ HRAS ▸ CAPN2 ▸ CP ▸ PAK1 ▸
PTGS1 ▸ ALOX5 ▸ FXYD1 ▸ PTHLH ▸ GRB7 ▸ VDR ▸ CSH2 ▸
NR4A1 ▸ FMR1 ▸ FGB ▸ CAPN6 ▸ C1orf228 ▸ WNT16 ▸ SPP2 ▸
TACR1 ▸ FUT2 ▸ BMP2 ▸ CDH1 ▸ VASP ▸ PDGFA ▸ CDH5 ▸
ANPEP ▸ DPM2 ▸ IRS1 ▸ SOAT1 ▸ MYO16 ▸ ITGA5 ▸ CXCL2 ▸
SLPI ▸ HCG11 ▸ DUOX1 ▸ FUT5 ▸ KSR2 ▸ FCER2 ▸ DPM1 ▸
SMAD4 ▸ MTA3 ▸ TPT1 ▸ CAPN9 ▸ FOXO1 ▸ NAMPT ▸ F7 ▸
FCGR2B ▸ HCG24 ▸ HCG18 ▸ MTA1 ▸ SMAD2 ▸ CD44 ▸ CDC42 ▸
FUT7 ▸ MTA2 ▸ APOE ▸ MAP2K5 ▸ CEACAM6 ▸ FOXP3 ▸ CEBPA ▸
HCG21 ▸ GAL ▸ ELF5 ▸ RABEPK ▸ PTPN22 ▸ CAPN12 ▸ ATP8A2 ▸
F10 ▸ HCG17 ▸ CXCL13 ▸ MBP ▸ ALX4 ▸ CCL4 ▸ GIP ▸
PAK4 ▸ CAPN1 ▸ DNASE1 ▸ HBD ▸ AGTR1 ▸ HCG20 ▸ BPI ▸
SMAD7 ▸ PAK3 ▸ VAV1 ▸ SMAD6 ▸ PARK2 ▸ CAPN13 ▸ PAK6 ▸
MAP2K6 ▸ PAK2 ▸ DNASE2 ▸ GRPR ▸ SERPINB2 ▸ CD69 ▸ SMAD5 ▸
CSH1 ▸ CD83 ▸ ADAM19 ▸ TMSB4X ▸ TNP2 ▸ CD86 ▸ TSC22D3 ▸
OXA1L ▸ HCG22 ▸ IDO1 ▸ MAP2K3 ▸ CCL5 ▸ FUT10 ▸ MEFV ▸
TNP1 ▸ CTGF ▸ ELAVL1 ▸ MAPKAPK2 ▸ S100A9 ▸ CPB2 ▸ HMGB3 ▸
MAP2K4 ▸ PGP ▸ CYP19A1 ▸ ELF2 ▸ HMGB2 ▸ HCG16 ▸ F2RL2 ▸
SCARB1 ▸ JAK1 ▸ CAPN5 ▸ PROK1 ▸ TBP ▸ NLRP3 ▸ FUT9 ▸
TNFSF11 ▸ HCG4 ▸ CPB1 ▸ CAPN11 ▸ LBP ▸ IFIH1 ▸ PITX1 ▸
JAK3 ▸ NFKBIZ ▸ NPY4R ▸ KDR ▸ FUT8 ▸ ADAM10 ▸ BCR ▸
FUT3 ▸ HCG15 ▸ MPG ▸ ADRA2C ▸ P2RY12 ▸ GABBR2 ▸ MTNR1B ▸
TAS2R16 ▸ CCL16 ▸ MTNR1A ▸ RXFP4 ▸ TAS2R43 ▸ HCAR2 ▸ GNAI3 ▸
TAS2R31 ▸ S1PR2 ▸ SSTR3 ▸ C5AR1 ▸ HTR1A ▸ SSTR4 ▸ TAS2R50 ▸
S1PR5 ▸ ADRA2B ▸ CCR6 ▸ SSTR5 ▸ HTR1B ▸ NPBWR2 ▸ KNG1 ▸
BDKRB1 ▸ P2RY4 ▸ RXFP3 ▸ NPBWR1 ▸ LPAR5 ▸ CCL28 ▸ HCAR3 ▸
HRH4 ▸ ADORA3 ▸ P2RY13 ▸ C3AR1 ▸ OPRL1 ▸ TAS2R46 ▸ NMU ▸
S1PR4 ▸ TAS2R5 ▸ CCR1 ▸ CCR2 ▸ ANXA1 ▸ NPB ▸ PTGDR2 ▸
GNAI2 ▸ INSL5 ▸ CCL25 ▸ SUCNR1 ▸ HTR1F ▸ ADORA1 ▸ DRD4 ▸
MT-RNR2 ▸ GRM4 ▸ S1PR3 ▸ GNAI1 ▸ HTR5A ▸ SSTR1 ▸ GALR2 ▸
DRD2 ▸ GABBR1 ▸ NMUR1 ▸ GRM6 ▸ HEBP1 ▸ TAS2R41 ▸ PPBP ▸
PPY ▸ NPY1R ▸ CCR10 ▸ NPY5R ▸ OPRD1 ▸ PTGER3 ▸ GPER1 ▸
TAS2R14 ▸ TAS2R7 ▸ CCR4 ▸ APLNR ▸ U2AF1 ▸ TAS2R19 ▸ TAS2R39 ▸
TAS2R30 ▸ GRM3 ▸ GNB1 ▸ GNG2 ▸ CHRM4 ▸ HCAR1 ▸ GRM8 ▸
CCR8 ▸ DARC ▸ PNOC ▸ OPRK1 ▸ XCR1 ▸ MCHR1 ▸ CX3CR1 ▸
PDYN ▸ GRM7 ▸ TAS2R3 ▸ NMUR2 ▸ TAS2R20 ▸ PENK ▸ TAS2R1 ▸
NPY2R ▸ FPR1 ▸ OXGR1 ▸ TAS2R8 ▸ TAS2R13 ▸ TAS2R10 ▸ CCL27 ▸
PYY ▸ MCHR2 ▸ TAS2R45 ▸ OXER1 ▸ S1PR1 ▸ HRH3 ▸ PMCH ▸
ADRA2A ▸ HTR1E ▸ TAS2R60 ▸ CCR7 ▸ CHRM2 ▸ FPR3 ▸ CCL19 ▸
SSTR2 ▸ TAS2R40 ▸ GNAT3 ▸ HTR1D ▸ BDKRB2 ▸ GALR1 ▸ CCR9 ▸
TAS2R38 ▸ TAS2R9 ▸ TAS2R4 ▸ GALR3 ▸ TAS2R42 ▸ GRM2 ▸ DRD3 ▸
Data information
Please see the Gene Interactions Track Manual.