Gene interactions and pathways from curated databases and text-mining

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IL13 — IL5

Text-mined interactions from Literome

Suchin et al., J Am Acad Dermatol 2001 (Eosinophilia...) : Increased interleukin 5 production in eosinophilic Sézary syndrome : regulation by interferon alfa and interleukin 12
Foster et al., Immunol Rev 2001 (Asthma...) : Regulation of IL-5 and eotaxin levels within the lung by IL-4 and IL-13 allows Th2 cells to elegantly co-ordinate tissue and peripheral eosinophilia
Pope et al., J Allergy Clin Immunol 2001 (Pulmonary Eosinophilia) : IL-5 is required for IL-13 to induce eosinophilia throughout the lung, whereas eotaxin regulates the distribution of airway eosinophils
Nielsen et al., Blood 2002 (Lymphoma, T-Cell, Cutaneous) : Transfection of tumor cells with dominant negative Stat3 almost completely blocks IL-5 production and strongly inhibits IL-13 production, whereas IL-6 production is unaffected
Mattes et al., Curr Drug Targets Inflamm Allergy 2003 (Inflammation) : Recent studies also indicate that IL-5 and eotaxin, through eosinophils, may regulate Th2 cell function and IL-13 production from this lymphocyte
Yang et al., J Allergy Clin Immunol 2003 (Bronchial Hyperreactivity...) : Eotaxin-2 and IL-5 cooperatively promoted eosinophil accumulation, IL-13 production, and AHR to methacholine
Melk et al., Transplantation 2004 (Growth Disorders...) : During rhGH therapy in children with transplants, interleukin (IL)-2 production increased threefold at 4 weeks, and IL-4 and IL-13 increased by 70 % at 12 weeks
Edwan et al., Immunol Res 2007 (Asthma) : pUMVC3-hFLex treatment prevented the development of goblet cell hyperplasia and subepithelial fibrosis, and significantly reduced serum levels of IL-4 and IL-5 , and increased serum IL-10 levels ( p < 0.05 ) with no effect on serum IL-13
Haber et al., Exp Parasitol 2009 (Hyperalgesia...) : Leishmania major : interleukin-13 increases the infection induced hyperalgesia and the levels of interleukin-1beta and interleukin-12 in rats
Hammer et al., Microbiol Immunol 2008 : Oil B inhibited the production of all cytokines except IL-10, oil X inhibited TNF-alpha, IL-6 and IL-10, oil A inhibited TNF-alpha and IL-6, oil C inhibited IL-5 and IL-6 and oil Z inhibited IL-13 only
Tweyongyere et al., BMC infectious diseases 2011 (Pregnancy Complications, Parasitic...) : There was some evidence that maternal infection intensity was positively associated with cord blood IL-5 and IL-13 responses to SWA, and IL-5 responses to SEA, and that this association was modified by treatment with praziquantel
Higaki et al., Clin Exp Allergy 2012 (Eosinophilia...) : LPS pre-treatment enhanced SEB induced IL-5, IL-13 and IL-17A production in diclofenac treated DNPCs, while addition of PGE ( 2 ) inhibited IL-5 , IL-13 and IFN-? production ... LPS alone induced IL-5, IL-13 and IFN- ? production by diclofenac treated DNPCs, while the addition of EP2 and EP4 receptor-selective agonists, as well as PGE ( 2 ) itself, inhibited IL-5 and IL-13 production
Swain et al., Proc Natl Acad Sci U S A 1981 : We conclude that the C.C3.11.75 TRF activity is not due to interleukin 1 or to interleukin 2 but to a third factor provisionally designated as ( DL ) TRF
Zaitseva et al., Infect Immun 1995 : Gamma interferon ( IFN-gamma ), interleukin-2 (IL-2), IL-4, and IL-5 induction was assayed by mRNA-specific PCR and by enzyme linked immunosorbent assay and bioassay for protein production
Ochensberger et al., Blood 1996 : Furthermore, although some IL-13 is produced in response to C5a in the presence of IL-5 , GM-CSF, IGF-1 or IL-1 beta, IL-3 is by far the most effective