Liu et al., Cytokine 2005
:
MEK1/2 and nuclear factor kappa B (NF-kappaB) inhibitors ( U0126 and TLCK, respectively ) blocked the ability of b-FGF to induce NRP-1 mRNA expression, but inhibition of JNK ( SP600125 ) or PI3-kinase activity ( wortmannin ) did not
Schramek et al., Lab Invest 2009
(Fibrosis...) :
Basal and OSM induced NRP1 mRNA expression, as well as TGF-beta1 induced NRP2 mRNA and protein expression were partially mediated by MEK1/2-ERK1/2 signaling