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FGFR3 — PTX4

Text-mined interactions from Literome

Satoh et al., J Neurochem 1991 : The dose-response curves for the PTX induced increases in [ 3H ] ACh release and in [ Ca2+ ] i were depressed by removing extracellular Ca2+ or by decreasing extracellular Na+ concentrations ... It appears that at high concentrations PTX increases the release of [ 3H ] ACh by directly increasing the influx of Ca2+ into synaptosomes and by releasing Ca2+ from intracellular storage sites via an Na(+)-Ca2+ exchange mechanism
Kupchik et al., Proc Natl Acad Sci U S A 2008 (Synaptic Transmission) : We show that PTX enhances ACh and glutamate release ( in mice and crayfish, respectively ) and, most importantly, alters the time course of release without affecting Ca ( 2+ ) currents
Silinsky et al., Br J Pharmacol 1989 : Pertussis toxin ( PTX ) , which blocks certain classes of guanine nucleotide binding proteins ( G proteins ), consistently blocked the inhibitory effects of adenosine ( 100 microM-250 microM ) on quantal acetylcholine (ACh) secretion in rat phrenic nerve hemidiaphragm preparations
Santos et al., J Neurochem 1998 : The effect of adenosine on the [ 3H ] ACh release may be due to a direct inhibition of N-type Ca2+ channels and/or secondary to the inhibition of phospholipase C and involves the activation of PTX-sensitive G proteins