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MGP — TNF

Text-mined interactions from Literome

Cola et al., Biochem Biophys Res Commun 2004 (Calcinosis) : The effects of ox-LDL, but not TNFalpha , on MGP and BMP2 expression were inhibited by pretreatment of cells with an antibody directed at LOX-1, a lectin-like receptor for ox-LDL ( 10 microg/mL )
Lin et al., Ann Otol Rhinol Laryngol 1998 (Otitis Media with Effusion) : In this study, the effects of TNF-alpha on mucous glycoprotein (MGP) secretion from cultured chinchilla middle ear epithelial cells were examined, and TNF-alpha was found to stimulate MGP secretion in a time- and concentration dependent manner ... The addition of the protein kinase C inhibitor 1- ( 5-isoquinolinylsulfonyl ) -2-methylpiperidine ( H-7 ) to the culture significantly blocked TNF-alpha induced MGP secretion, while the calmodulin inhibitor N- ( 6-aminohexyl ) -5-chloro-1-naphthalenesulfonamide ( W-7 ) did not ... This suggests that TNF-alpha stimulates MGP secretion via a protein kinase C-dependent mechanism