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SLC9A3 — TNF

Text-mined interactions from Literome

Khan et al., Nephron 2002 (Body Weight...) : Selective induction of NHE-3 and TNF-alpha, and their reversal by cox-2 inhibition, suggest a cox-2 dependent regulation of NHE-3 , which possibly involves TNF-alpha released from the site of inflammation and not from the kidney in colitis
Amin et al., Am J Physiol Cell Physiol 2006 : IFN-gamma and TNF-alpha regulate human NHE3 gene expression by modulating the Sp family transcription factors in human intestinal epithelial cell line C2BBe1 ... Our data indicate that IFN-gamma and TNF-alpha may repress the NHE3 promoter activity in C2BBe1 cells by PKA mediated phosphorylation of Sp1 and Sp3 transcription factors
Siddique et al., Scand J Gastroenterol 2009 (Colitis, Ulcerative...) : These findings suggest a role of TNF-a in the regulation of NHE-3 expression in IBD