Gene interactions and pathways from curated databases and text-mining

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COA3 — LDLR

Text-mined interactions from Literome

Yu-Poth et al., J Nutr 2004 (Carcinoma, Hepatocellular...) : The present study was conducted to examine the effects of CLA on LDL receptor (LDLr) expression in HepG2 cells, and to evaluate whether the sterol response element binding protein 1 ( SREBP-1 ) and acyl CoA : cholesterol acyltransferase ( ACAT ) were involved in the regulation of LDLr expression by CLA
Yu-Poth et al., J Nutr 2005 : The objective of this study was to investigate the effect of individual PUFAs on LDL receptor (LDLr) expression in human fibroblasts and HepG2 cells, and to evaluate whether acyl CoA : cholesterol acyltransferase ( ACAT ) and sterol regulatory element binding protein 1 ( SREBP-1 ) were involved in the regulation of LDLr expression by fatty acids
Fung et al., J Biol Chem 1980 : In contrast, polyoxyethylated cholesterol stimulated LDL receptor activity, inhibited cholesterol ester formation mediated by LDL and 25-hydroxycholesterol, and inhibited the activity of acyl-CoA : cholesterol acyltransferase in cell extracts