Gene interactions and pathways from curated databases and text-mining

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CCNE1 — CDC34

Pathways - manually collected, often from reviews:

  • BioCarta cyclin e destruction pathway: FBW7/SKP1/CUL1/CDC34 complex (FBXW7-SKP1A-CUL1-CDC34) → Cyclin E (CCNE1) (protein ubiquitination, activates)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *