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ANGPT2 — INS

Text-mined interactions from Literome

Ma et al., Am J Physiol Cell Physiol 2004 : Thus the Cl- -dependent effects of ANG II on Ca2+ transients may be mediated , at least in part, by a Cl- -dependent Ins ( 1,4,5 ) P3 accumulation in VSMC
Nazari et al., J Med Invest 2007 (MAP Kinase Signaling System) : From these data in L6 myotube, we conclude that Ang II negatively regulates the insulin signal not through MMP signaling pathway but specifically through MMP independent ERK1/2 activation pathway, providing an alternative molecular mechanism for angiotensin induced insulin resistance
Diamond-Stanic et al., Arch Physiol Biochem 2010 : These results indicate that Ang II inhibits distal insulin signalling and insulin stimulated glucose transport in isolated mammalian skeletal muscle, and that this effect is partially mediated by ROS
Siebelmann et al., J Recept Signal Transduct Res 2010 : ANG II and IV as well as their non-degradable analogs SARILE and Nle-ANG IV increased the glucose induced insulin release in a bell shaped way ; the maximum effect was at approximately 1 nM
Ketsawatsomkron et al., Vascul Pharmacol 2010 (Insulin Resistance) : Transfection of VSMC with PTP-1B antisense oligonucleotide markedly reduced the effects of Ang II on insulin signaling
Pu et al., Am J Physiol Heart Circ Physiol 2011 : Insulin and NO increased the secretion of ANG II into the culture media by 2- and 2.5-fold ( P < 0.05 ), respectively, whereas treatment of cells with ANG II uncovered the motogenic effect of NO ( 1.4-fold above control, P < 0.05 ) and decreased the levels of PTP1B to 45 % of control ( P < 0.05 )
Anderson et al., Kidney Int 1996 : To explain the mechanism of these additive effects, we investigated the action of Ang II on insulin signaling and the effect of insulin on Ang II AT1 receptor mRNA expression
Fliser et al., Hypertension 1997 : Angiotensin II (Ang II) modulates the tissue response to insulin ( insulin sensitivity ), but the effect of Ang II on the secretion of insulin has not been investigated thus far ... Ang II affects both the basal ( nonpulsatile ) and the pulsatile component of spontaneous insulin secretion and the glucose stimulated insulin secretion in humans