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Arbabi et al., Arch Surg 1999
:
Platelet activating factor (PAF) activates
p38 , an important intracellular signal transduction kinase, and primes human mononuclear cells for the production of interleukin 8 (IL-8), a potent chemoattractant and activator of neutrophils
Partrick et al., Arch Surg 2000
:
The
p38 mitogen activated protein kinase ( MAPK ) is
activated by
PAF stimulation
Zhao et al., Int J Cardiol 2010
(MAP Kinase Signaling System) :
Furthermore, PAF induced apoptosis and release of cytochrome c from mitochondria was blunted by SB203580, and
PAF induced enhancement of
p38 activity was also attenuated by BAPTA/AM
Zhang et al., J Biol Chem 1999
:
The
PAF induced
p38 and ERK pathways appeared to be preferentially regulated by RGS16 and RGS1, respectively