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C5 — EPHB2

Text-mined interactions from Literome

Niculescu et al., Immunopharmacology 1999 : Raf-1 and ERK1 were also activated by C5b-9 in human AEC in a G protein dependent manner
Cybulsky et al., Am J Pathol 1999 (Glomerulonephritis) : Phosphorylated EGF-R bound the adaptor protein, Grb2, and the EGF-R-selective tyrphostin, AG1478, blocked the C5b-9 induced ERK2 phosphorylation, [ ( 3 ) H ] AA release, and PGE ( 2 ) production by 45 to 65 %, supporting a functional role for EGF-R kinase in mediating the activation of these pathways
Badea et al., J Neuroimmunol 2003 : C5b-9 activated ERK1 , which in turn activated Elk1 in myotubes
Niculescu et al., J Immunol 1997 : ERK1 activity was 2-fold increased by C5b-9 at 2 min and by C5b-7 at 10 min, over the C5b6 level
Rus et al., Immunopharmacology 1997 : C5b-9 but not C5b6 induced activation of both ERK1 and c-jun NH2 terminal kinases 1 ( JNK1 ) in OLG