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CLDN4 — EPHB2
Text-mined interactions from Literome
Cohen et al., PloS one 2010
(MAP Kinase Signaling System...) :
Expression of
claudin 4 , claudin 18, and occludin was significantly lower, and activation of JNK and
ERK signaling pathways was significantly
increased in 2CLP monolayers, relative to sham monolayers ... Inhibition of
ERK , not JNK, significantly
increased TER and expression of
claudin 4 in 2CLP monolayers, and prevented significant differences in claudin 18 expression between 2CLP and sham monolayers
Okumura et al., J Gastroenterol 2010
(Gastrointestinal Neoplasms...) :
Inhibition of
MEK-ERK signaling
mediated up-regulation of E-cadherin and
claudin-4 , and/or decreased expression of matrix metalloproteinases ( MMPs ) such as MMP-2 and MMP-9, play a role in the TZD induced inhibition of cancer cell invasion