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EPHB2 — ITGAV

Text-mined interactions from Literome

Das et al., J Biol Chem 2004 (Breast Neoplasms...) : Furthermore, OPN induces alpha(v)beta(3) integrin/EGFR mediated ERK1/2 phosphorylation and AP-1 activation
Rucci et al., J Cell Sci 2005 (Bone Resorption) : Engagement of alphavbeta3 integrin triggered ERK1/2 phosphorylation, but the underlying molecular mechanism was surprisingly independent of the well known Shc/Ras/Raf-1 cascade, and of phosphorylated MAP/ERK kinase (MEK)1/2, so far the only recognized direct activator of ERK1/2
Scarlett et al., J Endocrinol 2008 (MAP Kinase Signaling System...) : To establish whether transient ERK activation via the integrin alpha(V)beta ( 3 ) cell surface receptor mediated these effects, MG-63 cells were pretreated for 30 min with the specific MAPK kinase inhibitor, U0126 ( 1 microM ), or an anti-integrin alpha(V)beta ( 3 ) -blocking antibody
Pavasant et al., Oral Dis 2008 (MAP Kinase Signaling System) : The anti-alphavbeta3 integrin antibody could also inhibit ERK activation, suggesting the possible role of alphavbeta3 integrin on the regulation of ERK and cell migration