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EPHB2 — KLF2

Text-mined interactions from Literome

Woo et al., Circ Res 2008 (Diabetes Mellitus...) : Shear stress induced extracellular signal regulated kinase ( ERK ) 5 activation and the consequent regulation of Kruppel-like factor 2 and endothelial nitric oxide synthase expression represents one of the antiinflammatory and vascular tone regulatory mechanisms maintaining normal endothelial function
Sunadome et al., Dev Cell 2011 : Remarkably, Klf2 and Klf4 expression are also upregulated during differentiation in an ERK5 dependent manner, and knockdown of Klf2 or Klf4 specifically suppresses muscle cell fusion
Heo et al., Circ J 2011 (Atherosclerosis...) : Here, we propose a new signaling pathway involving d-flow induced EC inflammation via PKC?-ERK5 interaction mediated downregulation of KLF2/eNOS stability, which leads to PKC? mediated p53-SUMOylation and EC apoptosis