Gene interactions and pathways from curated databases and text-mining

◀ Back to P2RX7

P2RX7 — P2RY2

Text-mined interactions from Literome

D'Alimonte et al., Int J Immunopathol Pharmacol 2007 : To further investigate the mechanisms by which P2X(7) receptors mediated the P2Y(2) mRNA up-regulation, the cells were pre treated with the chelating agent EGTA, or with inhibitors of mitogen activated kinase ( MAPK ) ( PD98059 ) or protein kinase C, ( GF109203X ) ... We conclude that activation of P2X(7) receptors in astrocytes enhances P2Y(2) mRNA expression by a mechanism involving both calcium influx and PKC/MAPK signalling pathways
Mishra et al., J Cell Sci 2011 : These results suggest that the activation of P2X(7)R increases surfactant secretion by releasing ATP from AEC I and subsequently stimulating P2Y(2) receptors in AEC II