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EGF — IL8

Text-mined interactions from Literome

Wu et al., Am J Physiol Lung Cell Mol Physiol 2001 : These data demonstrate that Utah Valley PM can induce IL-8 expression partially through the activation of the EGF receptor signaling
Subauste et al., Int Immunopharmacol 2001 : Effects of tumor necrosis factor-alpha, epidermal growth factor and transforming growth factor-alpha on interleukin-8 production by, and human rhinovirus replication in, bronchial epithelial cells ... Furthermore, EGF and TGF-alpha enhanced tumor necrosis factor-alpha (TNF-alpha) induced IL-8 production by BEAS-2B cells
Tan et al., Sheng Li Xue Bao 2002 : The results of the experiments showed that VIP exerted an inhibitory effect on the secretion of IL-1 and IL-8 from unstimulated and O3-stressed BECs, VIP also decreased the secretion of IL-5 from O3-stressed BECs ; EGF promoted secretion of IL-1 and IL-8 from unstimulated BECs, but decreased the secretion of ILs from O3-stressed BECs ; ET-1 and CGRP enhanced the secretion of IL-1, IL-5, and IL-8 from unstimlated BECs, CGRP also increased the secretion of ILs from O3-stressed BECs
Bancroft et al., Int J Cancer 2002 (Carcinoma, Squamous Cell...) : In our study, we examined the effect of EGF and antagonists of EGFR, PI3K and MEK on NF-kappaB and AP-1 activation and IL-8 and VEGF expression in HNSCC cell lines UM-SCC-9 and 11B in which EGFR is overexpressed and activated ... Recombinant EGF induced EGFR phosphorylation, activation of NF-kappaB and AP-1 reporter genes and IL-8 and VEGF expression, indicating that EGFR can mediate coactivation of both transcription factors and cytokine genes in HNSCC
Halpern et al., J Pediatr Gastroenterol Nutr 2003 (Disease Models, Animal...) : We have shown in previous studies that proinflammatory interleukin-18 and interleukin-12 are up-regulated in the ileum of rats with experimental NEC and that epidermal growth factor (EGF) reduces the development of disease
Hamilton et al., Clin Exp Allergy 2003 (Asthma...) : Using H292 cells, EGF and H2O2 increased IL-8 gene expression and release and this was completely suppressed by the EGFR-selective tyrosine kinase inhibitor, AG1478, but only partially by dexamethasone ... EGF also significantly stimulated IL-8 release from asthmatic or normal primary epithelial cell cultures established from bronchial brushings
Zhao et al., J Biol Chem 2004 : Furthermore, inhibition of the EGF receptor by AG1478 significantly reduced NT-induced IL-8 promoter activity and IL-8 secretion
Pawliczak et al., J Biol Chem 2004 : Methyl arachidonyl fluorophosphate, a cPLA2 inhibitor, inhibited the effect of A23187 and of EGF on both IL-8 and COX-2 reporter gene activity, steady state levels of IL-8 and COX-2 mRNA, and IL-8 and COX-2 protein expression ... Small inhibitory RNAs directed against PPAR-gamma1 and -gamma2 blunted the effect of A23187 and of EGF on IL-8 and COX-2 protein expression ... Moreover small inhibitory RNAs directed against cPLA2 decreased the effect of A23187 and EGF on IL-8 and COX-2 protein expression
Lewkowicz et al., Immunol Lett 2005 (Inflammation) : Moreover, EGF enhanced IL-8 production by TNF-alpha primed PMN
Hamilton et al., Eur Respir J 2005 (Asthma) : Neither salbutamol nor dexamethasone inhibited EGF stimulated IL-8 release
Chokki et al., Life Sci 2006 : TNF-alpha and epidermal growth factor (EGF) stimulated IL-8 secretion in a time- and concentration dependent manner
Nakanaga et al., Am J Physiol Lung Cell Mol Physiol 2007 (Carcinoma, Squamous Cell...) : First, we show that EGF receptor (EGFR) and MAP kinase ERK1/2 are involved in IL-8 expression by these stimuli
Darbonne et al., J Clin Invest 1991 : Their binding of IL-8 is rapidly reversible and does not result in receptor internalization, although bound IL-8 is resistant to extraction by pH 3 buffer at 5 degrees C. 125I-IL-8 binding to red cells was not inhibited by epidermal growth factor or interleukin 1, but was inhibited by monocyte chemotactic peptide-1, which is not a neutrophil chemotaxin, but is a member of the same family of polypeptides as IL-8
Tanida et al., Digestion 2010 : Here, we focus on the mechanisms of IL-8 induced HB-EGF-CTF signaling, which is involved in cytoprotection and cellular repair
Yang et al., Exp Eye Res 2010 : Neither EGF nor WIN induced any increases in IL-6 and IL-8 release
Zhao et al., J Biol Chem 2011 (Colitis...) : The dual role of NT in inflammation and healing is demonstrated in models of colitis induced by Clostridium difficile toxin A and dextran sulfate sodium, respectively, and involves NF-?B dependent IL-8 expression and EGF receptor mediated MAPK activation in human colonocytes
Zhang et al., J Cell Physiol 2012 (Carcinoma, Non-Small-Cell Lung...) : We initially found that EGF could directly stimulate IL-8 production, proliferation, and bio-behaviors of lung cancer cells through the activation of EGFR, PI3K, Akt, and Erk signal pathway ... EGF stimulated IL-8 production, phosphorylation of Akt and Erk, and cell proliferation and movement could be inhibited by EGFR inhibitor ( Erlotinib ), PI3K inhibitor ( GDC-0941 BEZ-235 and SHBM1009 ), and ERK1/2 inhibitor ( PD98059 )
Grob et al., J Biol Chem 1990 : The binding of MDNCF/IL-8 to human neutrophils is not inhibited by interleukin-1 alpha, tumor necrosis factor-alpha, insulin, or epidermal growth factor
Schuerer-Maly et al., Immunology 1994 : In T84 cells IFN-gamma and epidermal growth factor (EGF) stimulated IL-8 secretion synergistically with TNF-alpha, whereas in SW620 cells this synergism occurred only between IFN-gamma and TNF-alpha