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IL8 — PROK1

Text-mined interactions from Literome

Maldonado-Pérez et al., Biochim Biophys Acta 2009 (Adenocarcinoma...) : Here we demonstrate that PROK1 induces the expression of IL-8 , a chemokine with angiogenic properties, in endometrial epithelial Ishikawa cells stably expressing prokineticin receptor 1 and in human first trimester decidua ... We also show that IL-8 promoter activity is induced by PROK1 and that this requires the presence of AP1 and NFAT motifs ... A modulatory role for RCAN1-4 is demonstrated by RCAN1-4 overexpression which results in the inhibition of PROK1 induced IL-8 expression whereas reduction in RCAN1-4 endogenous expression results in an increase in PROK1 induced IL-8 production
Gorowiec et al., Am J Pathol 2011 (Endometritis...) : In addition, we demonstrate that PROK1 increases the expression of chemokine C-C motif ligand 20, IL-6, IL-8 , prostaglandin synthase 2, and prostaglandin E ( 2 ) and F ( 2a ) secretion