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EGR1 — FASLG

Text-mined interactions from Literome

Rengarajan et al., Immunity 2000 : Sequential involvement of NFAT and Egr transcription factors in FasL regulation ... Activation of FasL occurs via the NFAT dependent induction of Egr3, as demonstrated by the ability of exogenously provided NFATp to restore Egr dependent FasL promoter activity in DKO lymph node cells
Yang et al., J Biol Chem 2002 : HIV Tat binds Egr proteins and enhances Egr dependent transactivation of the Fas ligand promoter ... A Tat molecule containing a single amino acid substitution that results in the loss of transactivation activity for the HIV long terminal repeat still binds Egr-3 but can no longer enhance Egr mediated transactivation of the FasL promoter
Droin et al., Mol Cell Biol 2003 : Egr family members regulate nonlymphoid expression of Fas ligand , TRAIL, and tumor necrosis factor during immune responses
Yoo et al., J Biol Chem 2004 (Carcinoma, Hepatocellular...) : Finally, we found that the carboxyl terminus of HBx was necessary and sufficient for FasL induction as well as activation of Egr
Mittelstadt et al., Mol Cell Biol 1998 : These studies identify a critical Egr family binding site in the fasL promoter and demonstrate that activation induced Egr-3, but not Egr-1 , directly upregulates fasL transcription in response to activating stimuli
Mittelstadt et al., J Biol Chem 1999 : We previously identified a Fas ligand regulatory element (FLRE) in the Fas ligand (fasL) promoter that binds Egr family proteins and demonstrated that Egr-3 ( PILOT ) but not Egr-1 ( NGFI-A, Krox-24, Tis-8, and Zif-268 ) induces transcription of fasL