Gene interactions and pathways from curated databases and text-mining

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FASLG — THY1

Text-mined interactions from Literome

Kojima et al., Int Immunol 2000 (Calcium Signaling) : It is shown that glycophosphatidylinositol linked surface glycoprotein Thy-1 preferentially activates FasL-Fas- but not perforin mediated cytotoxicity
Haeryfar et al., Immunol Cell Biol 2005 : In contrast, Fas ligand expression and function was not affected by Thy-1 blockade
Cohen et al., Am J Respir Cell Mol Biol 2009 : Thy1 mediated FasL induction has been reported in T cells through the use of anti-Thy1 ( G7 ) ... Moreover, we directly show that Thy1 activation induces FasL up-regulation ... Initially, Thy1 activation causes translocation of FasL to the membrane surface, and later induces de novo synthesis of FasL at the mRNA and protein levels