Gene interactions and pathways from curated databases and text-mining

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HRAS — VEGFA

Text-mined interactions from Literome

Casanova et al., Cancer Res 2002 (Cell Transformation, Neoplastic...) : This study reports that activated Ha-ras results in a dramatic induction of EGFR in epidermal tumor cells and provides experimental evidence that EGFR signaling is responsible for Ha-ras dependent vascular endothelial growth factor ( VEGF ) induction, as well as for the repression of other angiogenic factors such as angiopoietin 1
Shu et al., Mol Cell Biol 2002 (Carcinoma...) : VEGF stimulation of T24 cells caused a slow and sustained accumulation of Ras-GTP and phosphorylated extracellular signal regulated kinase ( phospho-ERK ) compared with that after EGF treatment ... Small interfering RNA ( siRNA ) that targets SPK1, but not SPK2, blocks VEGF induced accumulation of Ras-GTP and phospho-ERK in T24 cells
Basu et al., PloS one 2011 (Kidney Neoplasms) : The overexpression of PRAS40 in renal cancer cells significantly down-regulated CNI- and H-Ras induced VEGF transcriptional activation
Grugel et al., J Biol Chem 1995 (Cell Transformation, Neoplastic) : Both v-Ha-Ras and v-Raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells
Larcher et al., Cancer Res 1996 (Carcinoma, Squamous Cell...) : Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels