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CSF1 — RHOA
Text-mined interactions from Literome
Kim et al., J Clin Invest 2006
(Bone Resorption) :
DEX specifically arrested
M-CSF activation of
RhoA , Rac, and Vav3, each of which regulate the osteoclast cytoskeleton
Kim et al., Ann N Y Acad Sci 2007
:
Dexamethasone specifically arrests
M-CSF activation of
RhoA , Rac, and Vav3, each of which regulate the osteoclast cytoskeleton
van Helden et al., PloS one 2012
:
Finally, GM-CSF stimulation, during macrophage and osteoclast differentiation, leads to high expression of Rac2, while
M-CSF induces high levels of
RhoA , showing that these cytokines induce a distinct pattern