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HMOX1 — SFN

Text-mined interactions from Literome

Shan et al., Cardiovasc Toxicol 2010 (Vasculitis) : Interestingly, SFN significantly induced HO-1 and TR expression down-regulated by LPS
Ping et al., Brain Res 2010 (Disease Models, Animal...) : Sulforaphane (SFN) , an isothiocyanate found in cruciferous vegetables, has cytoprotective effects against oxidative stress and its effect was mediated by NF-E2 related factor-2 (Nrf2), a transcription factor, and heme oxygenase 1 (HO-1) which is one of Nrf2 downstream target genes
Lee et al., J Korean Med Sci 2011 : Knockdown of Nrf2 with siRNA attenuated SFN induced heme oxygenase-1 (HO-1) up-regulation
Lo et al., Toxicol Appl Pharmacol 2013 (Breast Neoplasms) : In contrast, DIM+SFN or TCDD+SFN induced NQO1 and HMOX1 mRNA expression to levels higher than SFN alone, which was prevented by RNAi mediated knockdown of AHR