UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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PCNA — PPP2R1A

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Intact Interaction: Complex of 306 proteins (association, pull down) Komarova et al., Mol Cell Proteomics 2011
IRef Intact Interaction: Complex of 400 proteins (association, cross-linking study) Humphries et al., Science signaling 2009

Text-mined interactions from Literome

Lacey et al., Proc Natl Acad Sci U S A 1999 : Cyclin dependent kinase control of centrosome duplication
Skoczylas et al., Virology 2005 : PP2A dependent transactivation of the cyclin A promoter by SV40 ST is mediated by a cell cycle regulated E2F site
McCourt et al., Cell cycle (Georgetown, Tex.) 2013 : PP2A ( Cdc55 ) regulates G 1 cyclin stability
Arnaud et al., Chromosoma 1998 : In vertebrates, Plks participate in centrosome maturation and spindle assembly, as well as the activation of the Cdk1/cyclin B complex