Gene interactions and pathways from curated databases and text-mining

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IFNG — SNAP25

Text-mined interactions from Literome

Daniel et al., J Cell Physiol 2006 (Burns...) : SNAP also dose-dependently suppressed IFN-gamma and IL-2 ( Th1 ), but not IL-4 and IL-10 ( Th2 ) production ... Delaying the addition of SNAP to the cultures by 24 h prevented the suppression of IFN-gamma production
Sosroseno et al., Anaerobe 2009 : The results showed that in A. actinomycetemcomitans LPS stimulated cells, SNAP enhances iNOS activity but inhibits the levels of specific IgG2a and IFN-gamma suggesting a Th1 response
Athanassakis et al., Eur Cytokine Netw 1995 (Hypersplenism...) : We also show that IFN-gamma increases the numbers of Tcyt/sup ( Ly2 positive cells ) and TH ( L3T4 positive cells ) in the spleen of virgin mice but not in pregnant mice
Taylor-Robinson et al., Immunol Cell Biol 1997 : The proliferation of, and IL-2-IFN-gamma production by, naive CD4+ T cells from normal spleens activated with Con A in vitro can be similarly inhibited by SNAP