Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
ABL1
→
Complex of ABL1-RB1
(decreases, ABL1/RB1 Activity)
Evidence: c-Abl tyrosine kinase activity is blocked by pRb, which binds to the c-Abl kinase domain (Welch and Wang, 1995).
OpenBEL Selventa BEL large corpus:
Complex of ABL1-RB1
→
RB1
(decreases)
Evidence: Phosphorylation of pRb disrupts the c-Abl:pRb complex and releases active c-Abl (Welch and Wang, 1995).